Did the RNA Vax Produce Negative Heritable Changes?

 The article by Tomislav Domazet-Lošo in Genes (MDPI, 2022) argues that mRNA from COVID-19 vaccines meets all structural criteria for retroposition via LINE-1 retrotransposons. It emphasizes that no experimental studies have ruled out genomic integration and calls for urgent research. The author suggests that if integration occurs in germline cells, heritable spike protein production is biologically plausible.

https://doi.org/10.3390/genes13050719

Walter Doerfler’s article in Virus Research (2021) presents evidence that adenoviral DNA and SARS-CoV-2 RNA fragments can integrate into mammalian genomes. He discusses epigenetic consequences and the possibility of germline integration, though not proven. He calls for post-vaccination genomic surveillance and emphasizes that chance mechanisms in biology can lead to unexpected outcomes.
https://doi.org/10.1016/j.virusres.2021.198466

The Authorea preprint by Kyriakopoulos, McCullough, Nigh, and Seneff (2022) expands on retroposition risks, arguing that vaccine mRNA is structurally compatible with genomic integration. It highlights the vulnerability of stem and germline cells and calls for toxicity evaluations. The authors suggest that heritable effects are possible and underexplored.
DOI: 10.22541/au.166203678.82079667/v1

The MDPI article in Molecular and Cellular Biochemistry (2023) by Seneff, Nigh, Kyriakopoulos, and McCullough reviews potential risks of mRNA vaccines, including spike protein toxicity, immune dysregulation, and genomic integration. It discusses HLA disruption and autoimmune risks and calls for high-resolution molecular monitoring. The paper supports the plausibility of heritable spike production.
DOI: 10.7759/cureus.34872

The Journal of Precision Biosciences article (2025) by Rashid, Amin, Tufael, and Rahman argues that synthetic mRNA may embed into the human exome and interfere with transcription. It raises concerns about HLA scrambling, oxidative stress, and DNA damage. The authors advocate for ethical oversight and genomic safety studies, suggesting that